v:kit for HPLC and GC IQ/OQ/PQ

June 2006

 

Dear Reader,

Welcome to the v:kit newsletter. In this publication we aim to keep users and distributors updated on the latest developments in the equipment qualification arena.

In this issue

·  Answers to frequently asked questions

·  New extended wavelength test

·  Compliance watch

·  Low risk v:kit evaluation

·  Attend the next v:kit web conference



New extended wavelength test

As part of the continual improvement of v:kit an extended UV wavelength accuracy test has been introduced to HPLC v:kit

In response to customer demand the new test, based on the existing v:kit model, measures wavelength accuracy at 205nm.
To enable this test on your current HPLC v:kit2 system, simply purchase the UV Detector extended refill kit.

Ordering details:

Part number:VKIT2-X16
Description:UV Detector extended refill kit
Price:165.00 GBP

Part number:VKIT2-UP
Description:HPLC v:kit2 upgrade (required if you have v:kit1)
Price:200.00 GBP(if purchased with VKIT2- X16)

Normal distributor discounts are available.

order now!



Compliance watch

FDA cites repeat deviations of 21 CFR part 211 in warning letter for Croatian pharmaceutical manufacturing facility

The warning letter includes the following observation:

3. The calibration of instruments was not always conducted at suitable intervals. 21 CFR 211.160(b)(4)
...a [redacted] used for [redacted] during the qualification of [redacted] were not qualified or calibrated. Please provide an impact assessment for the [redacted] processed in these [redacted]. Your response indicates you will qualify and calibrate these pieces of equipment and identify all critical and non-critical GMP equipment in order to have a more comprehensive qualification and calibration program. However, failure to calibrate and qualify a [redacted] and [redacted] was the subject of the first three items on the last FDA 483 issued 8/30/02. Repeat observations indicate that your corrective action in 2002 was not adequate.

View the full warning letter



Low risk v:kit evaluation

Designed to offer you a low risk way of using the full v:kit product, a special evaluation version is now available.

It contains everything supplied with the full Initia starter kits — software, reference standards, SOPs and consumables. The only difference is that the kit has a 3-month expiry period.

Ordering details:

Part No: VKIT2-E64
Description: HPLC evaluation kit
Price: £330.00

Part no: VKIT-EGC
Description: GC evaluation kit
Price: £330.00

Order an evaluation v:kit today



Attend the next v:kit web conference

The next v:kit web conference has been scheduled

The web conference will be held on Wednesday, 28- June-2006 at 14:00 BST (GMT +1).
To register log on instructions simply register using the link below.

Register for the web conference

Answers to frequently asked questions

Here are some answers to questions we are frequently asked in relation to v:kit

Question:
Who can qualify analytical instruments, is it true that only the instrument vendors should perform operational qualification (OQ)?

Answer:
The equipment user has the ultimate responsibility for the equipment qualification. This does not mean that the user must perform the OQ, although there is no technical reason why they cannot. If the user chooses to have the OQ delivered by either by a service provider or the instrument vendor then it is their responsibility to ensure that the quality of the qualifications and importantly their consistency across instruments are adequate.

Question:
Has v:kit been approved by the FDA or any other regulatory authority?

Answer:
Regulatory authorities do not approve qualification products like v:kit. What the FDA and other have done is audit pharmaceutical laboratories that use v:kit for their HPLC and GC qualifications. To our knowledge none of these audits have resulted in any negative comments on v:kit and the qualifications delivered with it.

Question:
Are v:tools (the qualification tools available as part of the v:kit range) NIST traceable?

Answer:
v:tools are are supplied with UKAS traceable calibrations. UKAS (the United Kingdom Accreditation Service) and the NIST National Voluntary Laboratory Accreditation Program (NVLAP) are both signatories to the ILAC agreement. This means that there is mutual recognition between UKAS and NIST NVLAP traceable calibrations. For further details of the mutual recognition see http://ts.nist.gov/ts/htdocs/210/214/docs/mra. htm

View additional FAQs

 

quick links...

newsletter archive

v:kit website

validation questions

more about nlg

contact the author




Join our mailing list!

email: info@v-kit.com

phone: +44 (0)1625 574633

web: http://www.v-kit.com